for Wii: tales of symphonia: dawn of the new world wariorware for comp: WoW wait for the new starcraft and im pretty sure theres alot more :/ but thats just in my opinion
I don't play PC games, but for Wii, let's say. Mario Kart Wii Super Smash Bros Brawl Link's Crossbow Training
You absolutely must play the Wii version of Resident Evil 4. Honestly, there's nothing like it, it just works so well.
CoD 4 - modern warfare Intense but short plot. never tried the multi player(cause mine is *ahem*) but i heard its really rad as well !!
If you're into RTS's or castle sims you could try any of the Stronghold games... They're dated but Stronghold Crusader is still one of the best ones IMHO
For the computer, old school FTW! Starcraft! Always fun for me >_< Diablo II, ladder reset is coming "as early as late April," quoted from Blizzard forums.