You can compare your high school life to the ... well, DNA double helix structure. And if you keep going, you can form chromosomes furthermore. Anyway, here is a good resource of reference. Hope it will help you out : http://en.wikipedia.org/wiki/Meaning_of_life
I once wrote a paper that related life's journey to walking through the halls of my high school. Basically, walking was parallel to living and things like doors and trashcans were opportunities and obstacles. I thought it was pretty well thought out, but my teacher didn't agree and I got like a B-. Anyway, hope that helps.
A whole wiki article on the number 42? And well, you need ot be a little more specific. There is soo much you could write about high school life. The possibilities really are endless. Are you looking for a certain aspect of it?